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Cell viability Sulforodamine B (SRB) assay was performed to determine the effect of CB-839 (Cayman CAT NO: 22038) targeting glutathione inhibition, Polydatin (Sigma-Aldrich CAT NO: 15721-25G) targeting the activity of glutathione in antioxidative mechanism, IKE (Cayman CAT NO: 27088) targeting xCT transporter inhibition, 5-FU (Koak Farma 1000 mg/20 mL sterile), CB-839 and 5-FU, Polydatin and 5-FU and IKE and 5-FU combinations on cell viability in HCT-116 CRC cells

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